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   Rated 3 out of 5

   Maximilian – September 25, 2025

   Anabolic Steroids In Women

   An Overview of Anabolic Steroids (AAS)

   Anabolic–androgenic steroids (commonly called AAS
   or “steroids”) are synthetic derivatives of testosterone that
   can promote muscle growth, increase strength,
   and enhance physical performance. While they have legitimate medical applications—such as treating hormone deficiencies, certain types of anemia, or
   delayed puberty—they are also used off‑label by athletes, bodybuilders, and others seeking a performance or aesthetic advantage.

   Below is a balanced look at the benefits, risks, and practical considerations for anyone thinking about using AAS.

   The goal is to provide information that can help you make an informed decision while keeping
   safety in mind.

   —

   1. Medical Uses

   Condition How AAS Helps Typical Dose & Duration

   Hypogonadism (low testosterone) Restores normal hormone levels, improves libido, mood,
   bone density, and muscle mass 100–200 mg/week of testosterone enanthate/isodur;
   4–12 weeks

   Anabolic steroid deficiency in children with
   chronic disease Promotes growth, prevents weight loss, improves quality of life 0.1–0.2 mg/kg/day; duration varies

   Severe wasting from chronic illness or HIV Increases appetite, preserves lean body mass 200–300 mg/week of nandrolone
   decanoate; 8–12 weeks

   The above doses are examples; actual regimens depend on clinical judgment
   and monitoring.

   —

   4. Potential Side‑Effects & Contra‑Indications

   System Possible Adverse Effect When to Stop / Seek Care

   Hepatobiliary (oral agents) Elevated transaminases, jaundice,
   cholestasis, hepatic steatosis ALT/AST >3× ULN;
   any signs of liver dysfunction

   Cardiovascular Hypertension, fluid retention, arrhythmias, myocardial ischemia
   New or worsening HTN (>180/110), heart failure symptoms

   Endocrine / Metabolic Hyperglycemia, insulin resistance, dyslipidemia HbA1c >9% despite therapy; uncontrolled glucose

   Renal Acute kidney injury (especially with diuretics) Creatinine rise >30% from baseline

   Dermatologic Acneiform rash, pruritus Severe itching or rash covering >50% BSA

   Hematologic Leukopenia, neutropenia ANC Note: For patients with baseline HbA1c ≥8%,
   a more aggressive glucose monitoring protocol is recommended.

   —

   4. Monitoring Schedule

   Parameter Frequency Notes

   Fasting blood glucose (FBG) Every 3–4 h during first 24 h,
   then q6–12 h If >200 mg/dL → insulin therapy

   Random blood glucose Same as FBG For patients
   with hypoglycemia risk

   HbA1c At admission (baseline) To stratify risk

   Serum electrolytes (Na⁺, K⁺, Mg²⁺, Ca²⁺) q12 h during first
   48 h; then daily Correct deficits promptly

   BUN/Creatinine Daily Monitor renal function

   Lactate Every 6–8 h Elevated lactate may indicate
   impaired perfusion or sepsis

   Urine output Hourly 2)
   • Broad‑spectrum antibiotics within 1 hour
   • Vasopressor if MAP 2 mmol/L
   THEN start vasopressor (norepinephrine 0.05–0.1 µg/kg/min)
   IF persistent hypotension after fluids
   add phenylephrine or epinephrine as per protocol

   C. Fluid Resuscitation

   If fluid deficit >2 L and lactate >4 mmol/L
   give 30 mL/kg crystalloid over 1 hour
   Monitor urine output; target >0.5 mL/kg/h

   3. Laboratory Work‑up

   Test Frequency (initial, then) Rationale

   CBC with diff, BMP, lactate Initial + every 4–6 h until stable Detect sepsis,
   electrolyte shifts, organ dysfunction

   Coagulation panel (PT/INR, aPTT, fibrinogen, D‑dimer) Initial + q12 h
   if coagulopathy suspected Monitor DIC

   Blood cultures (2 sets from separate sites) 2–4 h after antibiotics Identify bacteremia

   Urine culture After antibiotic initiation; repeat if fever
   persists >48 h Detect urinary source

   Sputum Gram stain & culture If productive cough Guide anti‑pneumococcal therapy

   Serum electrolytes (Na, K, Cl) q6–q12 h as indicated Adjust
   fluid/diuretic therapy

   Arterial blood gases If oxygenation deteriorates or after ventilatory changes

   —

   5. Follow‑Up and Discharge Planning

   Re‑evaluation of renal function at least once weekly; consider dose adjustments for
   diuretics, ACEI/ARB, NSAIDs.

   Monitoring of electrolytes in the first week post‑discharge; educate patient on signs of hyper/hypokalemia, hyponatremia.

   Fluid intake guidelines: 1–1.5 L/day (depending on BP and edema status) or per nephrology recommendation.

   Medication adherence counseling: importance of diuretics,
   ACEI/ARB, statins; avoid OTC NSAIDs.

   Lifestyle modifications: low‑sodium diet (

   anavar dosage men